Jen Crodelle
About me
I am an applied mathematician interested in using mathematical modeling and computer simulation to explore problems in neuroscience and uncover plausible mechanisms underlying biologically observed phenomena. I have also worked on problems in epidemiology, criminal justice, and chronic pain.
When not working on mathematical models, I enjoy reading and exploring the outdoors with my family!
Appointments
- Assistant Professor of Mathematics and Statistics, Middlebury College, 2020-present
- NSF Postdoctoral Fellow, Courant Institute of
Mathematical Sciences (NYU), 2017–2020
- Mentor: Dr. David McLaughlin
Education
- Ph.D. in Mathematics, Rensselaer Polytechnic
Institute (RPI), 2017
- Dissertation Advisors: Dr. Gregor Kovačič and Dr. David Cai
- B.S. in Applied Mathematics, Marist College, 2012
Grants & Funding
- NSF
EPSCoR Research Fellowship ($237K) | 2026–2027
- Project title: Building Mechanistic Models for the Interaction of Tau Protein and Neuronal Voltage
- Some details: This is a grant aimed at building a collaboration at the intersection of modeling neuron voltage dynamics and cellular transport using neurodegenerative diseases (tauopathies) as an application. See Neurological Disease Modeling page for more details.
- NIH R15 NCCIH
Grant ($540K) | 2025–2028
- Project title: Modeling mechanisms of interindividual variation in pain modulation by spinal cord stimulation
- Some details: This is a collaborative grant with Co-I’s at
University of Michigan aimed at using mathematical modeling to predict
mechanisms underlying the observed variability in pain relief
experienced across patients using spinal cord stimulation. See Pain Processing Dynamics page for more
details.
- Here is a story in the
- MAA NREUP
Award ($35K) | 2025
- Project title: Mathematical Modeling in Neuroscience. This grant provided funds to hire four undergraduate summer research assistants.
- Some details: This award supported four undergraduate summer research assistants to investigate the bifurcation in firing patterns generated in different gap-junction-coupled neurons.
- VBRN Project Award
($150K) | 2023-2025
- Project title: The role of inhibitory plasticity during development in the formation of orientation preference maps.
- Some details: This project aimed to understand how different inhibitory plasticity rules applied during development may affect the formation of the orientation-preference map in the adult mouse.
Selected Publications
Crodelle J., Dai W.P. Uncovering potential effects of spontaneous waves on synaptic development: The visual system as a model. PRX Life, 4, 013022 (2026).
Ginsberg A.G., Lempka S.F., Duan B., Booth V., Crodelle J. Mechanisms for dysregulation of excitatory-inhibitory balance underlying allodynia in dorsal horn neural subcircuits. PLoS Comput. Bio., 21(1): e1012234 (2025).
Du, X., Crodelle, J. et al. Biophysical modeling and experimental analysis of the dynamics of C. elegans body-wall muscle cells.PLoS Comput. Bio., 21(1): e1012318 (2025)
Crodelle J., Vanty C., Booth V. Modeling homeostatic and circadian modulation of human pain sensitivity. Front. Neurosci., 17, 1166203 (2023).
Crodelle, J. and McLaughlin, D. W. Modeling the role of gap junctions between excitatory neurons in the developing visual cortex. PLoS Comput. Bio., 17(7): e1007915 (2021).
Epstein, J.M., Hatna, E., Crodelle, J.. Triple contagion: a two-fears epidemic model J. of the Royal Soc. Inter., 18(181): 20210186 (2021).
(For a full list of publications, see my CV or Google Scholar.)
Contact
For potential research collaboration or inquiries from students, please contact me at:
- Email: jcrodelle [at] middlebury [dot] edu
- Office: Warner Hall 204, Middlebury College
- Phone: (802) 443-3122